When trying to open a company file, QuickBooks Error 6143 frequently arises because of file corruption or network problems. Damaged company files, unfinished QuickBooks installations, or issues with multi-user mode are typical culprits. The problem may also be caused by firewall or antivirus software preventing QuickBooks from accessing necessary files. Error 6143 can be fixed by using the verify and rebuild utilities to address file corruption, using the QuickBooks File Doctor tool, or restoring a backup of the company file. To guarantee correct access to the company file, consider reinstalling QuickBooks or modifying firewall and antivirus settings if the error continues.